Ischemic Skin Necrosis in Hepatorenal Syndrome Patient Secondary to Terlipressin
نویسندگان
چکیده
منابع مشابه
Severe ischemic bowel necrosis caused by terlipressin during treatment of hepatorenal syndrome
Terlipressin is a vasopressin analogue that is widely used in the treatment of hepatorenal syndrome or variceal bleeding. Because it acts mainly on splanchnic vessels, terlipressin has a lower incidence of severe ischemic complications than does vasopressin. However, it can still lead to serious complications such as myocardial infarction, skin necrosis, or bowel ischemia. Herein we report a ca...
متن کاملTerlipressin-Induced Ischemic Skin Necrosis: A Rare Association
BACKGROUND Terlipressin is a synthetic vasopressin analogue that is used in the treatment of bleeding esophageal varices and hepatorenal syndrome in patients with cirrhosis. Serious ischemic adverse events, such as skin necrosis involving the extremities, scrotum, trunk, and abdominal skin, are rarely observed. In the literature to date, 20 cases that developed ischemic skin necrosis due to ter...
متن کاملNoradrenaline or terlipressin for hepatorenal syndrome?
Hepatorenal syndrome is a condition associated with very high mortality that may be reverted in some cases with vasoconstrictors. Terlipressin has generally been considered standard treatment, but noradrenaline has been postulated as alternative. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified six systematic reviews including four pertinent rand...
متن کاملMeta-analysis: terlipressin therapy for the hepatorenal syndrome.
BACKGROUND The hepatorenal syndrome is a severe and well-known complication of end-stage liver disease, but its management is controversial. Recent reports have shown the efficacy of terlipressin therapy, a vasopressin analogue, in hepatorenal syndrome patients. AIM To evaluate the efficacy and safety of terlipressin in the treatment of hepatorenal syndrome. METHODS We performed a systemati...
متن کاملTerlipressin for hepatorenal syndrome: A meta-analysis of randomized trials.
BACKGROUND Hepatorenal syndrome (HRS) is a severe complication of end-stage renal disease whose management still constitutes a big challenge. Various approaches have been used for hepatorenal syndrome treatment, including vasoconstrictor therapy. Terlipressin, a vasopressin analogue, has frequently been used. AIM To evaluate the efficacy and safety of terlipressin in patients with HRS by perf...
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ژورنال
عنوان ژورنال: Journal of the College of Physicians and Surgeons Pakistan
سال: 2019
ISSN: 1022-386X,1681-7168
DOI: 10.29271/jcpsp.2019.06.s26